All type A influenza virus, including the cause seasonal epidemic in humans, the genetic extremely unstable and can quickly adapt to avoid the body's defense mechanisms (antibody) the (host). Virus-influenza virus have less mechanism for the "proofreading" or "repair the damage the structure" and improve the disability / differences that arise during replication. As a result of the differences that are not repaired, then the genetic composition of virus when the virus replicated change in humans and animals, and strain before antigenik replaced with new variants. Small changes that are constant and permanent, in the composition of influenza A virus antigenik known seb aga i "antigenic drift". Antigenik This drift can occur in the influenza virus types A and B.
virus-influenza virus antigenic changes in the permanent and quite often this causes a situation to monitor the WHO influenza program in the world in the WHO Global Influenza Program began in th. 1947. Every years after the monitoring on 4 WHO collaborative research centers that receive data from 112 institutions from 83 countries. WHO provides a reference to the influenza vaccine manufacturers to make the vaccine with the appropriate subtipe-subtipe the influenza virus circulation in the world. (Influenza vaccine recommendations)
Influenza viruses have characteristics of both the trigger sad very very health of the community. Influenza virus type A, including subtipe-subtipe from a different species (Avian and human), may change or the genetic material can be arranged and exchange new "reassort". The process of re-drafting of this genetic material known as "antigenic shift". Antigenik this shift will result in a new type of subtipe different from the second parent. Because the human population does not have any immunity against subtipe new, and there is no vaccine available to provide protection, antigenic shift in the history of the pandemic (epidemic highway), which is death. This especially appears when subtipe have new genes from the human influenza virus can spread from person to person during the period of ongoing.
Conditions that enable the emergence of antigenic shift have long known that involves human life, or live near cattle and domestic pigs. Easy because pigs are infected either from virus or from avian virus-mammals, including human influenza virus, the pig could act aga i seb media blender "mixing vessel" to confuse genetic material from human and avian viruses, which result in the emergence of new virus subtipe. Data that identify possible new second. Evidence that the learned, at least some of the 15 types of avian influenza virus that bersirkulasi in poultry populations could provide an infection in humans and humans can
virus-influenza virus antigenic changes in the permanent and quite often this causes a situation to monitor the WHO influenza program in the world in the WHO Global Influenza Program began in th. 1947. Every years after the monitoring on 4 WHO collaborative research centers that receive data from 112 institutions from 83 countries. WHO provides a reference to the influenza vaccine manufacturers to make the vaccine with the appropriate subtipe-subtipe the influenza virus circulation in the world. (Influenza vaccine recommendations)
Influenza viruses have characteristics of both the trigger sad very very health of the community. Influenza virus type A, including subtipe-subtipe from a different species (Avian and human), may change or the genetic material can be arranged and exchange new "reassort". The process of re-drafting of this genetic material known as "antigenic shift". Antigenik this shift will result in a new type of subtipe different from the second parent. Because the human population does not have any immunity against subtipe new, and there is no vaccine available to provide protection, antigenic shift in the history of the pandemic (epidemic highway), which is death. This especially appears when subtipe have new genes from the human influenza virus can spread from person to person during the period of ongoing.
Conditions that enable the emergence of antigenic shift have long known that involves human life, or live near cattle and domestic pigs. Easy because pigs are infected either from virus or from avian virus-mammals, including human influenza virus, the pig could act aga i seb media blender "mixing vessel" to confuse genetic material from human and avian viruses, which result in the emergence of new virus subtipe. Data that identify possible new second. Evidence that the learned, at least some of the 15 types of avian influenza virus that bersirkulasi in poultry populations could provide an infection in humans and humans can
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